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Diseasome of Inactivity

Physical inactivity increases the risk of type 2 diabetes cardiovascular disease, colon cancer, postmenopausal breast cancer, dementia, and depression. These prevalent chronic diseases are associated with an enhanced risk of premature morbidity and interact in notable ways: patients with type 2 diabetes have a markedly increased risk of CVD, Alzheimer’s disease and vascular dementia. Individuals with type 2 diabetes also have a high prevalence of affective illness, including major depression. In addition, patients with type 2 diabetes have an elevated risk of developing colon and breast cancer, as well as pancreatic, liver and endometrial cancer.

The diseasome of physical inactivity includes diseases with shared pathogenetic mechanisms. Independently of body mass index (BMI), physical inactivity is a risk factor for all-cause mortality. It is a striking feature that chronic systemic inflammation is associated with physical inactivity independent of obesity.

It appears that physical inactivity leads to the accumulation of visceral fat and the subsequent activation of a network of inflammatory pathways, which promote the development of insulin resistance, atherosclerosis, neuro-degeneration and tumour growth, and thereby the development of the diseases belonging to the diseasome of physical inactivity.

diagram diseasome of physical inactivity

Hypothesis: physical inactivity leads to the accumulation of visceral fat and consequently to the activation of a network of inflammatory pathways, which promote the development of insulin resistance, atherosclerosis, neuro-degeneration and tumour growth, leading to the development of ‘the diseasome of physical inactivity’ Pedersen (2011)

Assisted Mobility will encourage you to overcome suspicions of dependency that prevent the timely adoption of mobility aides that promote movement and ultimately contribute to health-span. More movement is critical to overcoming the negative impacts of sedentariness and leveraging the function of muscles as endocrine organs that support metabolic, neurological and immunoendocrine health.

2/50 Princes Highway Cobargo NSW 2550. Opposite Cobargo Doctors.